DNA from Mycobacterium tuberculosis Complex Identified in North American, Pre-Columbian Human Skeletal Remains
Identifieur interne : 001877 ( Main/Exploration ); précédent : 001876; suivant : 001878DNA from Mycobacterium tuberculosis Complex Identified in North American, Pre-Columbian Human Skeletal Remains
Auteurs : Mark Braun [États-Unis] ; Della Collins Cook [États-Unis] ; Susan Pfeiffer [Canada]Source :
- Journal of Archaeological Science [ 0305-4403 ] ; 1998.
English descriptors
Abstract
Mycobacterium tuberculosiscomplex DNA has been detected in two ancient, North American human bone samples, dating from the Pre-Columbian period. Using polymerase chain reaction (PCR) and DNA sequence analysis, diagnostic portions of the IS6110genomic element ofMycobacterium tuberculosishave been confirmed in a Canadian ossuary sample dating to the 15th centuryADas well as from a Middle Mississippian burial dating to the early 11th centuryad. Both specimens revealed lesions highly suggestive of tuberculosis. In the second case a soil sample, collected from the abdominal region of the burial, was assessed for possible soil contamination. These results add credence to the use of PCR as a tool in the investigation of infectious diseases in ancient human bone. They also provide additional evidence for the Pre-Columbian presence of tuberculosis in the New World.
Url:
DOI: 10.1006/jasc.1997.0240
Affiliations:
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Using polymerase chain reaction (PCR) and DNA sequence analysis, diagnostic portions of the IS6110genomic element ofMycobacterium tuberculosishave been confirmed in a Canadian ossuary sample dating to the 15th centuryADas well as from a Middle Mississippian burial dating to the early 11th centuryad. Both specimens revealed lesions highly suggestive of tuberculosis. In the second case a soil sample, collected from the abdominal region of the burial, was assessed for possible soil contamination. These results add credence to the use of PCR as a tool in the investigation of infectious diseases in ancient human bone. They also provide additional evidence for the Pre-Columbian presence of tuberculosis in the New World.</div></front></TEI><affiliations><list><country><li>Canada</li><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="Braun, Mark" sort="Braun, Mark" uniqKey="Braun M" first="Mark" last="Braun">Mark Braun</name></noRegion><name sortKey="Collins Cook, Della" sort="Collins Cook, Della" uniqKey="Collins Cook D" first="Della" last="Collins Cook">Della Collins Cook</name></country><country name="Canada"><noRegion><name sortKey="Pfeiffer, Susan" sort="Pfeiffer, Susan" uniqKey="Pfeiffer S" first="Susan" last="Pfeiffer">Susan Pfeiffer</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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